L. John Hoffer, MD, PhD

Speaker, 48th Annual International Orthomolecular Medicine Today Conference


Leonard John Hoffer is a Professor of Medicine at McGill University and Associate Professor in McGill’s School of Dietetics and Human Nutrition. He is a full-time investigator in the Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, and a Senior Physician in the Divisions of General Internal Medicine and Endocrinology in the JGH, where he serves on the nutritional support team.

Dr. Hoffer obtained his medical and subspecialty training in internal medicine at McGill, then a PhD in Human Nutrition at the Massachusetts Institute of Technology, Cambridge MA, a clinical fellowship in nutritional support at Harvard Medical School, and a post-doctoral fellowship in biochemistry at Brandeis University, returning to McGill in 1984 as an assistant professor. Dr. Hoffer’s research and clinical interests focus on the relationship between disease and malnutrition, the metabolic adaptation to starvation, and micronutrient metabolism in disease. He authored the chapter on the metabolic features of human starvation in the last several editions of the clinical nutrition textbook, Modern Nutrition in Health and Disease, and co-authored the chapter entitled “Enteral and parenteral nutrition therapy” in the 2015 edition of Harrison’s Principles of Internal Medicine, the world’s most prestigious medical textbook. In 2012 he was recipient of the Kursheed Jeejeebhoy Award and Plenary Lecture, Canadian Nutrition Society.

Presentation Abstract

Nutrient Synergy is Required to Prevent and Mitigate Acute and Chronic Diseases

“If the mind was simple enough to understand we would be too simple to understand it.” This aphorism applies as well to the myriad molecules our minds and bodies are made of,  and the myriad interactions among micronutrients and macromolecules that enable our organism to function more or less optimally. Biochemical and clinical research use reductionist tools that are powerful but blunt; they are about the only reliable ones we have. This presentation takes a glimpse beyond individual vitamin and nutritional mineral requirements to examine the broad implications of the complex and subtle interactions we know are constantly taking place amongst the nutrients, and offers some practical pointers for optimal overall nutrition.

Orthomolecular Medicine Hall of Fame

Inducted 2015