This conference brings together world-class scientists and clinicians to explore the metabolic, nutritional, and lifestyle drivers of brain ageing. Over one focused day, leading researchers will present the latest evidence, emerging biomarkers, and practical pathways that make prevention a reality, with measurable interventions practitioners can use right now.

This is for any clinician wishing to be up to date and ready to move beyond outdated narratives and step into a systems-based approach grounded in biology and evidence-based science.

Drawing directly from the research presented by our speakers, this conference will show you:

  • The emerging picture of amyloid, why the story has changed, and what the evidence now tells us about underlying pathology
  • An update on predictive biomarkers, from amyloid, p-tau and homocysteine
  • The central role of homocysteine as a causal and measurable driver of decline
  • The critical interaction between omega-3 and B vitamins that creates neuronal integrity
  • Why phospholipids form the backbone of healthy brain architecture
  • The impact of menopause, hormones and disrupted sleep on long-term cognitive resilience
  • The need for brain stimulation to build and maintain the neural network
  • The influence of sugar, ultra-processed food, insulin resistance and microvascular stress on the ageing brain
  • How ketones energise the brain when glucose transport is compromised
  • The growing evidence around periodontal, gut and microbial infections as hidden accelerants of inflammation
  • Why reducing oxidative stress, promoting glutathione, and plant-derived polyphenols are key for cellular protection
  • How nutritional biomarkers and real-world citizen science data from the COGNITION Biobank are helping to define personalised prevention

Speakers

Prof. Stephen Cunnane – Ketones, An Essential Brain Fuel

Dr. Simon Dyall – Why Phospholipids are a Brain Essential

Prof. Peter Garrard – Update on Amyloid and P-Tau Tests for Dementia Diagnosis

Dr. Deborah Gordon – The Role of Hormones, Menopause and the Brain

Dr. William Grant – Vitamin D, How Much for Brain Protection

Prof. William Harris – Omega-3 and B Vitamin Interactions

Prof. Karl Herrup – The Amyloid Anomaly

Patrick Holford – Nutritional Biomarkers for Cognition, The DRIfT Study Results

Dr. Konrad Kowalski – The Glutathione Index

Prof. Robert Lustig – Ultraprocessed Foods and Their Role in Dementia

Prof. Joshua Miller – Is Homocysteine Causative for Alzheimer’s

Dr. David Perlmutter – The Five Key Brain Defenders

Dr. Greg Potter – Sleep and Dementia

Prof. Jeremy Spencer – The Role of Plants, Antioxidants and Polyphenols for Cognitive Protection

Prof. Jonathan Stone – Amyloid Created by Vascular Disease and Infection

Assoc. Prof. David Vauzour – Microbial Infection, Gut and Gum Health and the Brain

Assoc. Prof. Tommy Wood – A Systems-Based Model of Cognitive Decline