Featured article | May 2024
Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements
Fekete M, Lehoczki A, Tarantini S, et al.
Nutrients 2023, 15(24), 5116
Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements
Discussed in the article:
- The use of vitamins, minerals, antioxidants, and other dietary supplements in mitigating cognitive decline, especially in aging individuals
- The outcomes of memory enhancement, attention improvement, executive function support, and neuroprotection through a systematic evaluation of various studies
- The interplay between nutritional supplementation and cognitive health, with emphasis oh the importance of dosage, bioavailability, and individual differences in response to supplementation
- Safety concerns and potential interactions with conventional treatments
- Nutrient dosing and findings including:
- Folic acid supplementation (400 µg/day) for 24 months significantly improved cognitive function and reduced blood biomarker levels of amyloid β protein (Aβ) in mild cognitive impairment.
- Daily supplementation of 75 mg resveratrol resulted in a significant improvement in overall cognitive performance among middle-aged women.
- Supplementation of 1000 mg/day of vitamin C, carotenoids, and alpha-lipoic acid resulted in significant improvement in attention, memory, and other observed cognitive tests.
“The comprehensive analysis presented in this paper underscores the profound significance of nutritional supplementation in the preservation of cognitive health, particularly in the context of aging. Vitamins, minerals, antioxidants, dietary polyphenols, carotenoids and omega-3 PUFAs emerge as pivotal elements that play varied and crucial roles in maintaining and enhancing cognitive function.”
